Human Bone Marrow Mononuclear Cells (BMMCs)
Human Bone Marrow Mononuclear cells (BMMC, BM MNC or BM-MNC), a mixed population of single nucleus cells including monocytes, lymphocytes, and hematopoietic stem and progenitor cells, which have a single round nucleus, are isolated from whole bone marrow aspirate by density gradient. This removes most of the erythrocytes and granulocytes, producing stable quality product.
All bone marrow sample is collected in heparin from fully consented IRB approved donors. Donors are tested negative of HIV, HBV and HCV.
Mononuclear cells are critical components of the immune system and play key roles in the humoral and cell-mediated immune responses. Hence these cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening. HumanCells provides highly pure population of BMMC, which are ideal for further isolations of specific cell types within the mononuclear fraction.