Cytokines and Growth Factors

Cytokines and Growth Factors Expressed in Human Cells

HumanCells provides high purity and high activity cytokines and growth factors that are produced from mammalian cells (HEK293T cells).

• Superior bioactivity
• Superior stability
• Endotoxin-free / Xeno-free
• Tag-free, native conformation

Our cytokines are 100% derived from HEK293T cells using new technology that greatly enhanced the expression level of cytokines for up to 100-fold higher titer than traditional method.  This technology enable us to provide customers with higher purity authentic human cytokines without introducing any additional purification tags throughout the whole production process.

Functional activities of human cytokines depend on proper folding, phosphorylation, disulfide bridge formation, and appropriate glycosylation or proteolytic processing. Ideally, recombinant human proteins  produced from human cells have human-specific post-transcriptional modifications, and are more authentic in terms of both physical properties and biochemical functions.

Table-1. Only HEK293T cells produce true active human specific cytokines

Cytokines prepared from bacteria (E. Coli) and other expression systems can not avoid endotoxin contamination. Even low levels of endotoxins can be toxic to cells or organisms.  Our HEK293T cells derived cytokines together with extensive purification methods offer researchers human cytokines exhibiting ultra-low levels of endotoxin.