Human Normal Peripheral Blood CD4+ T Helper Cells
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The CD4+ T cells, also known as T helper cells (Th cells), are a type of T cells that play an important role in the immune system, particularly in the adaptive immune system. The T helper cell recognizes a foreign antigens and regulate immune response through different cytokines secretion, causing the B cell proliferation and activation and growth of cytotoxic T cell activation.
Our Peripheral Blood CD4+ T helper cells are isolated from peripheral blood mononuclear cells by negative immunomagnetic selection. All peripheral blood is collected in acid-citrate-dextrose formula A (ACDA) by leukapheresis from fully consented IRB approved donors that are tested negative for HIV, HBV and HCV.
T cells Mature in the Thymus, and become CD4+ after gaining an affinity for the MHC II class receptor. Upon maturation, CD4+ T cells spread throughout the body and lymph nodes in its naïve form, awaiting the activation by the antigen each T cell receptor is pre-programmed to respond to.