Human Normal Peripheral Blood Mononuclear Cells (PBMC)
Human Peripheral Blood Mononuclear Cells (PBMCs) are blood cells with a single round nucleus. These cells include lymphocytes (T, B and NK cells), monocytes and dendritic cells. PBMCs are parts of the immune system which are critical to cell-mediated and humoral immunity.
Our Human PBMCs are isolated from normal healthy donor leukopaks collected in acid-citrate-dextrose formula A (ACDA) as an anticoagulant. All donors must be tested negative for HBV, HCV, HIV and Syphilis and are IRB consented.
Cryopreserved PBMCs can be stored in Liquid Nitrogen vapor phase for long-term storage. Storage in liquid phase nitrogen is NOT recommended. Short-term storage of cells (less than 2 weeks) at -80°C is acceptable but should be minimized to ensure maximum stability. Once thawed, samples must be used immediately, and can not be frozen again.
Also available from
Fisher Catalog No.:
- NC1681388 (PBMC-C10M)
- NC1814842 (PBMC-C20M)
- NC2110997 (PBMC-F50M)
- NC1814844 (PBMC-C100M)
- NC2101392 (PBMC-F100M)
- NC2101862 (PBMC-F300M)
- NC2101863 (PBMC-F500M)
- NC2101866 (PBMC-F2B)
- NC2101868 (PBMC-F4B)
Our Product was utilized in:
- Wu, Kerui, et al. "Engineering an active immunotherapy for personalized cancer treatment and prevention of recurrence." Science Advances 9.17 (2023): eade0625. https://www.science.org/doi/10.1126/sciadv.ade0625
- Mao, Chengqiong, et al. "Delivery of an ectonucleotidase inhibitor with ROS-responsive nanoparticles overcomes adenosine-mediated cancer immunosuppression." Science translational medicine 14.648 (2022):DOI:10.1126/scitranslmed.abh1261